The history of CBD
The roots of cannabisdiol can be traced back thousands of years. By the end of the first ice age, the source plants of the CBD compound Cannabis Sativa were shown to be one of the first crops to be planted early. In fact, we tend to think that the cultivation of cannabis is modern, which is usually related to the birth of agriculture from 12,000 to 10,000 years ago.
The astronomer Carl Sagan is a symbol of scientific credibility. He suggests that marijuana may be the world’s first crop, which led to the development of civilization itself. From a time perspective, it is clear that cannabis plants have been an integral part of human civilization since the beginning.
1.CBD history begins in the 1940s
Roger Adams, a chemist from Harvard University, was the first person to successfully extract CBD from cannabis plants. When he first did this in 1940, he did not know that he had successfully extracted a compound. Years later, Adams and other scientists realized what he did and began to study the possible benefits of the CBD.
The history of modern CBD began in 1946, when Dr. Walter S. Loewe conducted the first CBD test on experimental animals. These tests prove that the CBD will not adapt to the mental state. In the same year, Dr. Raphael Mechoulam identified the three-dimensional structure of the CBD, which is why he is often considered to be a scientist in the CBD. The primates continued to be studied in the 1960s. Finally, the British Pharmacopoeia published the first CBD oil for therapeutic use.
2.From the 40s to the 60s: The first discoveries
The CBD was first isolated from cannabis extract by a research team at the University of Illinois (USA) Department of Chemistry. In an article published in January 1940, they noted that cannabinol is very toxic, but not active in cannabis.
Despite the achievements of scientists in Illinois, they are not interested in other experts in this molecule. Finally, in 1963, chemist Raphael Mechoulam from the Hebrew University of Jerusalem determined its exact structure. In the second year, his research team achieved other achievements: the first separation of THC and the management of two cannabinoid compounds. As a result, the work of the expert and his team opened up new areas in the study of cannabinoid pharmacology.
3.70s: The therapeutic use of CBD began to be studied
In 1973, a group of Brazilian scientists announced that the CBD reduced or even prevented seizures caused by animal epilepsy, and this confirmed the patients with neurological diseases. Although most people who receive a dose of compound have some improvement, they still cannot be considered to be decisive. Just one year later, in 1974, researchers in the country first discovered that the anti-anxiety drug CBD attenuated the symptoms of the disease.
In the mid-1970s, other clinical trials demonstrated that administration of the compound reduced chemotherapy-induced nausea and vomiting as a new medical field. At this time, the test also found the sedative effect of this chemical. Some studies have confirmed that it can also improve sleep in patients with insomnia by confirming this phenomenon in animals.
4.80s and 90s: CBD treatment of mental illness and anxiety
Publications on the CBD have multiplied in the decade of the 1970s, but in the following years, publications have reduced interest in molecules. Despite this, some important breakthroughs have been made during the period.
Brazil continues to make progress: In 1980, in a small study conducted by Mechoulam in collaboration with São Paulo, it was first revealed that CBD can reduce paralysis in patients with epilepsy.
Another study in 1982 described the CBD as having an antipsychotic effect. Studies by a group of healthy volunteers have shown that the compound inhibits sensory changes, disintegration and refusal to communicate with others. However, it was not until 1995 that patients were publicly given CBD.
In the late 1990s, a group of researchers at the National Institute of Mental Health (USA) found that CBD is a powerful cellular antioxidant. Other subsequent studies have shown that this effect also confers neuroprotective properties. This means that the chemistry of cannabis transformation can reduce the degeneration of neurons that are transformed into diseases such as Alzheimer’s disease and Parkinson’s disease.
In the last few years of this period, another area has also made progress: the law. British leaders support voters in Alaska, Oregon and Washington to legalize medical marijuana. In 1998, pharmaceutical company GW Pharmaceuticals obtained a license to produce the drug Sativex, which has the same proportion of THC and CBD for the treatment of pain and cramps in patients with multiple sclerosis.
The Legalization of cbd
CBD is a naturally occurring substance in cannabis plants. Unlike cannabinoids, tetrahydrocannabinol does not have psychoactive activity. In short, THC is a substance contained in cannabis. On the other hand, the CBD has no effect on the spirit. But according to more and more medical professionals, the CBD does have legitimate medical uses.
Legalization of cannabis can be divided into: Legalization of recreational cannabis and legalization of medical marijuana.
The legalization of medical marijuana means that citizens can only obtain certain doses of marijuana or cannabinoid products from state-licensed pharmacies for medicinal purposes through medical cards issued by doctors according to local laws.
Legalization of marijuana according to link includes planting, selling, transporting and holding legalization.
The Netherlands had been tolerant of cannabis until February, when it was legalized. Uruguayan residents were able to buy and hold 40 grams of cannabis a month from a state-licensed pharmacy.
Trafficking and transportation are regulated by relevant laws and regulations, so-called legalization of cannabis does not mean that cannabis, like potatoes, can enter and leave every household freely.
Since then, the CBD has been integrated into a range of products. The shelves across the country are filled with soda, craft beer, chewing gum and CBD pet snacks. People who are not interested in taking cannabinoids can choose from CBD-rich personal care and beauty products, from razors to lipsticks. But what is confusing is: If the federal government cannabis is illegal, how is it sold in some non-legalized countries? What is the role of CBD? What can we get? The conflict between state and federal cannabis legislation and the conflict between new and old laws complicate matters.
The legality of marijuana in medical and recreational terms varies depending on its possession, distribution and cultivation, and how it is consumed and the medical conditions that can be used. These policies in most countries are subject to the United Nations Single Convention on Narcotic Drugs ratified in 961 and the 1971 Convention on Psychotropic Substances and the 1988 Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances.
Most countries prohibit the eucalypse of cannabis, however, many people adopt a decriminalization policy (usually similar to minor traffic violations). Other countries have more severe penalties, such as some Asian and Middle Eastern countries, even a small number of countries will be imprisoned for several years. Canada (effective October 17, 2018) and Uruguay are the only countries that legalize consumption and sales. In the United States, although the CBD is federally illegal, nine states and the District of Columbia have legalized the sale and consumption of the CBD. The courts in Georgia and South Africa ruled that individual planting and cannabis consumption were legalized, but sales were not legal. Many countries have also adopted a limited enforcement policy, specifically in Spain and the Netherlands, where licensed companies can sell cannabis.
Countries that have legalized the medical use of cannabis include Australia, Canada, Chile, Colombia, Germany, Greece, Israel, Italy, the Netherlands, Peru, Poland, Sri Lanka and the United Kingdom. Others have more restrictive laws that only allow the use of certain cannabinoid drugs, such as Sativex or Marinol. In the United States, 31 states and the District of Columbia have legalized the medical use of cannabis, but at the federal level its use remains prohibited for any purpose.
On December 10, 2013, Uruguay passed the Legalization of Cannabis Act, making it the first country in the world to legally produce and sell cannabis, providing for phased loosening of control over the sale and cultivation of cannabis, thus enabling better tracking and control, while at the same time reducing police spending on combating drug crimes and increasing tax revenues.
Canada will begin to legalize cannabis in July this year. Prime Minister Trudeau of the Canadian Liberal Party government made a statement on legalizing cannabis.
On the one hand, like Uruguay, Canadian anti-drug measures do not solve the problem of young people smoking cannabis, and many people have criminal records for growing, owning and smoking cannabis in small quantities.
The purpose of legalizing cannabis, on the other hand, is for public health and social order. The government’s income from the commercial activities of cannabis dealers should be used exclusively for treating addicts, helping people with mental illness, and for public health education.
Under the premise of cracking down on the illegal market and discovering the medical and industrial value of cannabis, the process of legalization of cannabis has been invaded by a large number of countries in recent years. According to national conditions, the legalization of medical cannabis, entertainment cannabis,industrial cannabis, decriminalization and CBD of cannabis extract are different.
At present, nearly 30 countries around the world legalize medical cannabis, including 29 states in the United States, Germany, Australia, Colombia and so on, China is only Yunnan and Heilongjiang Province, industrial cannabis legalization.